PPP1R16B Antibody - Cat. #: CSB-PA584562

SKU: CSB-PA584562

Size :100ul

Clone Number:

Aliases:ANKRD4 antibody; Ankyrin repeat domain containing protein 4 antibody; ankyrin repeat domain protein 4 antibody; Ankyrin repeat domain-containing protein 4 antibody; CAAX box protein TIMAP antibody; hTIMAP antibody; KIAA0823 antibody; PP16B_HUMAN antibody; PPP1R16B antibody; Protein phosphatase 1 regulatory inhibitor subunit 16B antibody; protein phosphatase 1, regulatory (inhibitor) subunit 16B antibody; TGF beta inhibited membrane associated protein antibody; TGF-beta-inhibited membrane-associated protein antibody; TIMAP antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q96T49

Immunogen:Synthesized peptide derived from internal of Human PPP1R16B.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function. Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation. Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1. Involved in the regulation of endothelial cell filopodia extension. May be a downstream target for TGF-beta1 signaling cascade in endothelial cells.

Cao W., Am. J. Physiol. 283:C327-C337(2002).
Nagase T., DNA Res. 5:355-364(1998).
Nakajima D., DNA Res. 9:99-106(2002).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PPP1R16B

Research Areas:Signal transduction