PPP1CA Monoclonal Antibody

SKU: BT-MCA4534

Size:100μL

Background:The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research_area:Signal Transduction

Target_protein:PPP1CA

applications:WB

Reactivity:Human

Clonality:Monoclonal

Clone ID:5E9

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:PPP1CA

Immunogen:Purified recombinant fragment of human PPP1CA expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):38kDa

UniProt accession:P62136

Synonyms:PP-1A, PPP1A, PP1alpha

GeneID:5499