PON2 antibody , Cat. # FNab06639

SKU: FNab06639

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.)

Background:This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.

Immunogen:paraoxonase 2

Synonyms:

Observed MW:39 kDa

Uniprot ID:Q15165

Reactivity:Human, Rat

Tested Application:ELISA, IHC, WB

Recommended dilution:WB: 1:200 - 1:2000; IHC: 1:50 - 1:200

Gene ID:5445

Research Area:Cardiovascular, Metabolism