POLR3F Antibody, HRP conjugated - Cat. #: CSB-PA884440LB01HU

SKU: CSB-PA884440LB01HU

Size :50ug

Clone Number:

Aliases:DNA directed RNA polymerase III 39 kDa polypeptide antibody; DNA directed RNA polymerase III 39 kDa polypeptide F antibody; DNA directed RNA polymerase III subunit F antibody; DNA directed RNA polymerase III subunit RPC6 antibody; DNA directed RNA polymerases III 39 kDa polypeptide antibody; DNA-directed RNA polymerase III subunit F antibody; DNA-directed RNA polymerase III subunit RPC6 antibody; MGC13517 antibody; Polr3f antibody; Polymerase (RNA) III (DNA directed) polypeptide F antibody; RNA polymerase III 39 kDa subunit antibody; RNA polymerase III C39 subunit antibody; RNA polymerase III subunit C6 antibody; RPC 39 antibody; RPC 6 antibody; RPC39 antibody; RPC6 antibody; RPC6_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9H1D9

Immunogen:Recombinant Human DNA-directed RNA polymerase III subunit RPC6 protein (1-270AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct RNA Pol III binding to the TFIIIB-DNA complex. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF- Kappa-B through the RIG-I pathway.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:POLR3F

Research Areas:Epigenetics and Nuclear Signaling