POLR2G Antibody, Biotin conjugated - Cat. #: CSB-PA018334LD01HU

SKU: CSB-PA018334LD01HU

Size :50ul

Clone Number:

Aliases:DNA directed RNA polymerase II 19 kDa polypeptide antibody; DNA directed RNA polymerase II subunit G antibody; DNA directed RNA polymerase II subunit RPB7 antibody; DNA-directed RNA polymerase II subunit G antibody; DNA-directed RNA polymerase II subunit RPB7 antibody; hRPB19 antibody; hsRPB7 antibody; MGC138367 antibody; MGC138369 antibody; POLR2G antibody; polymerase (RNA) II (DNA directed) polypeptide G antibody; RNA polymerase II 19 kDa subunit antibody; RNA polymerase II subunit B7 antibody; RPB19 antibody; RPB7 antibody; RPB7_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P62487

Immunogen:Recombinant Human DNA-directed RNA polymerase II subunit RPB7 protein (1-172AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA (By similarity). Binds RNA.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:POLR2G

Research Areas:Epigenetics and Nuclear Signaling