PLA2G2A Antibody, HRP conjugated - Cat. #: CSB-PA11209B0Rb

SKU: CSB-PA11209B0Rb

Size :50ug

Clone Number:

Aliases:EC 3.1.1.4 antibody; GIIC sPLA2 antibody; Group IIA phospholipase A2 antibody; membrane associated antibody; Modifier of MIN 1 mouse homolog antibody; MOM1 antibody; Non-pancreatic secretory phospholipase A2 antibody; NPS PLA2 antibody; NPS-PLA2 antibody; PA2GA_HUMAN antibody; Phosphatidylcholine 2-acylhydrolase 2A antibody; Phosphatidylcholine 2acylhydrolase antibody; Phospholipase A2 antibody; Phospholipase A2 group IIA (platelets, synovial fluid) antibody; Phospholipase A2 membrane associated antibody; Phospholipase A2 polypeptide B antibody; Phospholipase A2 synovial antibody; PLA2 antibody; PLA2B antibody; PLA2G2A antibody; PLA2L antibody; PLA2S antibody; PLAS1 antibody; RASF A antibody; sPLA2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P14555

Immunogen:Recombinant Human Phospholipase A2, membrane associated protein (21-144AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides (PubMed:2925633). Thought to participate in the regulation of phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Independent of its catalytic activity, acts as a ligand for integrins (PubMed:18635536, PubMed:25398877). Binds to and activates integrins ITGAV:ITGB3, ITGA4:ITGB1 and ITGA5:ITGB1 (PubMed:18635536, PubMed:25398877). Binds to a site (site 2) which is distinct from the classical ligand-binding site (site 1) and induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:25398877). Induces cell proliferation in an integrin-dependent manner (PubMed:18635536).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PLA2G2A

Research Areas:Cancer; Cardiovascular; Metabolism; Signal transduction