PKC zeta Polyclonal Antibody

SKU: E-AB-32609

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: PKC ζ

Target Synonym: 14-3-3-zetaisoform;AI098070;aPKCzeta;C80388;EC 2.7.11.13;KPCZ;nPKC zeta;nPKC-zeta;OTTHUMP00000001368;OTTHUMP00000044160;PKC 2;PKC ZETA;PKC2;Pkcz;PKCZETA;PKM-zeta;included;PRKCZ;Protein kinase C zeta;Protein kinase C zeta form;Protein kinase C zeta type;r14-3-3;R74924;zetaPKC

Research Areas: Cancer;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat;Monkey

Application: WB;IHC-p;IF

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q05513

Accession:

Background: This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme. Phosphorylates 'Ser-311' of RELA subunit of NF-kappa-B.PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Subunit of a quaternary complex that plays a central role in epithelial cell polarization.

Concentration: 1 mg/mL

Immunogen: Synthesized peptide derived from human PKC ζ around the non-phosphorylation site of Thr560.

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:100-1:300;IF 1:200-1:1000

Calculated MW: 68kDa

ObservedMW: 80kDa