PK3CB Polyclonal Antibody

SKU: BT-AP13075

Size:100μL

Background:This gene encodes an isoform of the catalytic subunit of phosphoinositide 3-kinase (PI3K). These kinases are important in signaling pathways involving receptors on the outer membrane of eukaryotic cells and are named for their catalytic subunit. The encoded protein is the catalytic subunit for PI3Kbeta (PI3KB). PI3KB has been shown to be part of the activation pathway in neutrophils which have bound immune complexes at sites of injury or infection. Alternative splicing results in multiple transcript variants.

Research_area:Cell biology; Immunology; Signal transduction

Target_protein:PIK3CB

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: P42338; Mouse: Q8BTI9; Rat: Q9Z1L0

Synonyms:Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform ;PI3-kinase subunit beta;PI3K-beta;PI3Kbeta;PtdIns-3-kinase subunit beta;EC 2.7.1.153;Phosphatidylinositol 4,5-b

GeneID:Human: 5291