PIM2 Polyclonal Antibody

SKU: E-AB-10916

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:PIM2

Target Synonym:OTTHUMP00000025825;Pim 2 oncogene;Pim 2h;Pim-2h;PIM2;PIM2 Oncogene;PIM2;Pim2h;Proto Oncogene PIM2;Proto-oncogene Pim-2 (serine threonine kinase);Serine/threonine kinase PIM2;Serine/threonine-protein kinase Pim-2

Research Areas:Cancer;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q9P1W9

Accession:

Background:This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival. Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression, the regulation of cap-dependent protein translation and through survival signaling by phosphorylation of a pro-apoptotic protein, BAD. Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase transcriptional activity.

Concentration:0.3 mg/mL

Immunogen:Recombinant protein of human PIM2

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:IHC 1:50-1:200

Calculated MW:

ObservedMW: