PIM1 Polyclonal Antibody

SKU: E-AB-10915

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:PIM1

Target Synonym:Oncogene PIM 1;Oncogene PIM1;PIM 1;pim 1 kinase 44 kDa isoform;Pim 1 kinase;pim 1 oncogene (proviral integration site 1);Pim 1 oncogene;PIM;PIM1;pim1 kinase 44 kDa isoform;PIM1;Pim2;PIM3;Proto oncogene serine/threonine protein kinase Pim 1;Proto-oncogene serine/threonine-protein kinase Pim-1;Proviral integration site 1;Proviral integration site 2

Research Areas:Cancer;Epigenetics and Nuclear Signaling;Signal Transduction;Stem Cells

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P11309

Accession:

Background:The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons.

Concentration:0.3 mg/mL

Immunogen:Recombinant protein of human PIM1

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:IHC 1:50-1:200

Calculated MW:

ObservedMW: