PIAS3 Antibody - Cat. #: CSB-PA896765DSR1HU

SKU: CSB-PA896765DSR1HU

Size :50ul

Clone Number:

Aliases:E3 SUMO protein ligase PIAS 3 antibody; E3 SUMO protein ligase PIAS3 antibody; E3 SUMO-protein ligase PIAS3 antibody; FLJ14651 antibody; OTTHUMP00000015586 antibody; OTTHUMP00000015587 antibody; PIAS 3 antibody; Pias3 antibody; PIAS3 protein antibody; PIAS3_HUMAN antibody; Protein inhibitor of activated STAT 3 antibody; Protein inhibitor of activated STAT protein 3 antibody; Protein inhibitor of activated STAT3 antibody; Zinc finger MIZ type containing 5 antibody; ZMIZ 5 antibody; ZMIZ5 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9Y6X2

Immunogen:Recombinant Human E3 SUMO-protein ligase PIAS3 protein (399-628AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PIAS3

Research Areas:Epigenetics and Nuclear Signaling; Cell biology