PI4K2B antibody , Cat. # FNab06425

SKU: FNab06425

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Together with PI4K2A and the type III PI4Ks(PIK4CA and PIK4CB) it contributes to the overall PI4-kinase activity of the cell. This contribution may be especially significant in plasma membrane, endosomal and Golgi compartments. The phosphorylation of phosphatidylinositol(PI) to PI4P is the first committed step in the generation of phosphatidylinositol 4,5-bisphosphate(PIP2), a precursor of the second messenger inositol 1,4,5-trisphosphate(InsP3). Contributes to the production of InsP3 in stimulated cells and is likely to be involved in the regulation of vesicular trafficking.

Immunogen:phosphatidylinositol 4-kinase type 2 beta

Synonyms:

Observed MW:50-54 kDa

Uniprot ID:Q8TCG2

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC, IF

Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200; IF: 1:20-1:200

Gene ID:55300

Research Area:Signal Transduction, Metabolism