PI 3 kinase p85 alpha Polyclonal Antibody

SKU: E-AB-70381

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:PI 3 kinase p85 alpha

Target Synonym:GRB1;p85 alpha;p85;P85A;Phosphatidylinositol 3 kinase associated p 85 alpha;Phosphatidylinositol 3 kinase regulatory 1;Phosphatidylinositol 3 kinase;regulatory subunit;polypeptide 1 (p85 alpha);Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha;Phosphatidylinositol 3-kinase regulatory subunit alpha;Phosphoinositide 3 kinase;regulatory subunit 1 (alpha);PI3 kinase p85 subunit alpha;PI3-kinase regulatory subunit alpha;PI3-kinase subunit p85-alpha;PI3K;PI3K regulatory subunit alpha;Pik3r1;PtdIns 3 kinase p85 alpha;PtdIns-3-kinase regulatory subunit alpha;PtdIns-3-kinase regulatory subunit p85-alpha

Research Areas:Cancer;Metabolism;Immunology;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P27986,P26450,Q63787

Accession:

Background:Phosphatidylinositol 3-kinase (PI3K) plays an important role in the metabolic actions of insulin and is required for adipogenesis. The PI3K pathway has also been identified as an important player in cancer development and progression. The Class IA PI3K heterodimer,which is composed of a P110 catalytic subunit and a P85 regulatory subunit,is activated upon association of the P85 subunit with upstream adaptor proteins or receptor tyrosine kinases. Mutations in PIK3R1 are implicated in cases of breast cancer and associated to SHORT syndrome.

Concentration:1.6 mg/mL

Immunogen:Recombinant protein corresponding to Human PI 3 Kinase p85 alpha.

Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification method:Affinity purification

Dilution:WB 1:500-1:2000

Calculated MW:85kDa

ObservedMW:95kDa