Phospho-VDR (Ser51) Antibody - Cat. #: CSB-PA160201

SKU: CSB-PA160201

Size :100ul

Clone Number:

Aliases:1 25 dihydroxyvitamin D3 receptor antibody; 1 antibody; 1,25 dihydroxyvitamin D3 receptor antibody; 1,25-@dihydroxyvitamin D3 receptor antibody; 25-dihydroxyvitamin D3 receptor antibody; Member 1 antibody; NR1I1 antibody; Nuclear receptor subfamily 1 group I member 1 antibody; PPP1R163 antibody; Protein phosphatase 1, regulatory subunit 163 antibody; VDR antibody; VDR_HUMAN antibody; Vitamin D (1,25- dihydroxyvitamin D3) receptor antibody; Vitamin D hormone receptor antibody; Vitamin D nuclear receptor variant 1 antibody; Vitamin D receptor antibody; Vitamin D3 receptor antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P11473

Immunogen:Peptide sequence around phosphorylation site of serine 51 (R-R-S(p)-M-K) derived from Human Vitamin D3 Receptor.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Nuclear hormone receptor. Transcription factor that mediates the action of vitamin D3 by controlling the expression of hormone sensitive genes. Regulates transcription of hormone sensitive genes via its association with the WINAC complex, a chromatin-remodeling complex. Recruited to promoters via its interaction with the WINAC complex subunit BAZ1B/WSTF, which mediates the interaction with acetylated histones, an essential step for VDR-promoter association. Plays a central role in calcium homeostasis.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:VDR

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Signal transduction