Phospho-TH (Ser40) Antibody - Cat. #: CSB-PA154990

SKU: CSB-PA154990

Size :100ul

Clone Number:

Aliases:Dystonia 14 antibody; DYT14 antibody; DYT5b antibody; EC 1.14.16.2 antibody; OTTHUMP00000011225 antibody; OTTHUMP00000011226 antibody; ple antibody; Protein Pale antibody; TH antibody; The antibody; TY3H_HUMAN antibody; TYH antibody; Tyrosine 3 hydroxylase antibody; Tyrosine 3 monooxygenase antibody; Tyrosine 3-hydroxylase antibody; Tyrosine 3-monooxygenase antibody; Tyrosine hydroxylase antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P07101

Immunogen:Peptide sequence around phosphorylation site of serine 40 (R-Q-S(p)-L-I) derived from Human Tyrosine Hydroxylase (TH).

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IF; IF:1:100-1:200

Background:The protein encoded by Tyrosine Hydroxylase is involved in the conversion of tyrosine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Vazin T, et al. Stem Cells. 2008 Jun;26(6):1517-25
Pistocchi A, et al. BMC Dev Biol. 2008 Mar 10;8:27
Fukakusa A, et al. J Pharmacol Sci. 2008 Feb;106(2):321-4.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:TH

Research Areas:Neuroscience?Cancer;Metabolism