Phospho-SUFU (Ser342) Antibody - Cat. #: CSB-PA229368

SKU: CSB-PA229368

Size :100ul

Clone Number:

Aliases:OTTHUMP00000020374 antibody; OTTHUMP00000020377 antibody; OTTHUMP00000020379 antibody; PRO1280 antibody; SU FU antibody; SU(F)U antibody; Su(fu) antibody; SUFU antibody; SUFU negative regulator of hedgehog signaling antibody; SUFU_HUMAN antibody; SUFUH antibody; SUFUXL antibody; Suppressor of Fused antibody; Suppressor of fused homolog (Drosophila) antibody; Suppressor of fused homolog antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UMX1

Immunogen:Peptide sequence around phosphorylation site of Serine 342 (A-P-S(p)-R-K) derived from Human Sufu.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:SUFU encodes a component of the Sonic hedgehog (SHH; MIM 600725)/Patched (PTCH; MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945; BCNS, MIM 109400; and GCPS, MIM 175700)

Zimmern P,et al.(2010) Neurourol Urodyn.29(5):715-8.
Wang C,et al. (2010) Development. 137(12):2001-9.
Rabasseda X.et al.(2010) Drug News Perspect.23(4):273-5.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:SUFU

Research Areas:Epigenetics and Nuclear Signaling;Cancer