Phospho-REL (Ser503) Antibody - Cat. #: CSB-PA299508

SKU: CSB-PA299508

Size :100ul

Clone Number:

Aliases:Avian reticuloendotheliosis antibody; C REL antibody; C Rel protein antibody; c Rel proto oncogene protein antibody; Oncogene REL antibody; Oncogene REL avian reticuloendotheliosis antibody; Proto-oncogene c-Rel antibody; REL antibody; REL_HUMAN antibody; v rel avian reticuloendotheliosis viral oncogene homolog antibody; v rel reticuloendotheliosis viral oncogene homolog antibody; V rel reticuloendotheliosis viral oncogene homolog (avian) antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q04864

Immunogen:Peptide sequence around phosphorylation site of serine 503 (T-S-S(p)-D-S) derived from Human Rel.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IF; IF:1:100-1:200

Background:The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 (PubMed 18037997)).

Baeuerle, P.A. and Henkel, T. (1994) Annu Rev Immunol 12, 141-79.
Baeuerle, P.A. and Baltimore, D. (1996) Cell 87, 13-20.
Haskill, S. et al. (1991) Cell 65, 1281-9.
Thompson, J.E. et al. (1995) Cell 80, 573-82.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:REL

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Signal transduction