Phospho-PAK1 (Thr212) Polyclonal Antibody

SKU: E-AB-21179

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Acetyl/Phospho/Methyl Antibodies

Abbreviation: PAKα (phospho Thr212)

Target Synonym: ADRB2;Alpha PAK;Alpha-PAK;MGC130000;MGC130001;p21 activated kinase 1;p21 protein (Cdc42/Rac) activated kinase 1;p21-activated kinase 1;p21/Cdc42/Rac1 activated kinase 1 (yeast Ste20 related);p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog;yeast);p65 PAK;p65-PAK;P68-PAK;PAK alpha;PAK-1;Pak1;PAK1;Paka;PAKalpha;Protein kinase MUK2;Rac/p21-activated kinase;Serine/threonine-protein kinase PAK 1;STE20 homolog yeast

Research Areas: Cancer;Cell Biology;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB;IHC-p

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q13153

Accession:

Background: The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.

Concentration: 1 mg/mL

Immunogen: Synthesized peptide derived from human PAKα around the phosphorylation site of Thr212

Buffer: PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000;IHC 1:100-1:300

Calculated MW: 61kDa

ObservedMW: 65kDa