Phospho-NTRK2 (Tyr706/Tyr707) Antibody - Cat. #: CSB-PA789970

SKU: CSB-PA789970

Size :100ul

Clone Number:

Aliases:AI848316 antibody; BDNF tropomyosine receptor kinase B antibody; BDNF/NT 3 growth factors receptor antibody; BDNF/NT-3 growth factors receptor antibody; Brain derived neurotrophic factor receptor antibody; C030027L06Rik antibody; EC 2.7.10.1 antibody; GP145 TrkB antibody; GP145-TrkB antibody; GP145-TrkB/GP95-TrkB antibody; GP95 TrkB antibody; Neurotrophic receptor tyrosine kinase 2 antibody; Neurotrophic tyrosine kinase receptor type 2 antibody; Neurotrophin receptor tyrosine kinase type 2 antibody; NTRK 2 antibody; Ntrk2 antibody; NTRK2_HUMAN antibody; Obesity, hyperphagia, and developmental delay, included antibody; RATTRKB1 antibody; Tkrb antibody; Trk B antibody; Trk-B antibody; TRKB antibody; TrkB tyrosine kinase antibody; TRKB1 antibody; Tropomyosin related kinase B antibody; tyrosine kinase receptor B antibody; Tyrosine receptor kinase B antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q16620

Immunogen:Peptide sequence around phosphorylation site of tyrosine 706/tyrosine 707 (T-D-Y(p)-Y(p)-R-V)derived from Human Trk B.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; IHC:1:50-1:100

Background:

Receptor for brain-derived neurotrophic factor (BDNF), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (NGF). Involved in the development and/or maintenance of the nervous system. This is a tyrosine-protein kinase receptor. Known substrates for the TRK receptors are SHC1, PI-3 kinase, and PLC-gamma-1.

Nakagawara A., Genomics 25:538-546(1995).
Shelton D.L., J. Neurosci. 15:477-491(1995).
Stoilov P., Biochem. Biophys. Res. Commun. 290:1054-1065(2002).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NTRK2

Research Areas:Others