Phospho-GRIN2B (Ser1303) Antibody - Cat. #: CSB-PA071137

SKU: CSB-PA071137

Size :100ul

Clone Number:

Aliases:AW490526 antibody; EIEE27 antibody; Glutamate [NMDA] receptor subunit epsilon 2 antibody; Glutamate [NMDA] receptor subunit epsilon-2 antibody; Glutamate Receptor Ionotropic N Methyl D Aspartate 2B antibody; Glutamate Receptor Ionotropic N Methyl D Aspartate subunit 2B antibody; Glutamate receptor ionotropic NMDA2B antibody; Glutamate receptor subunit epsilon 2 antibody; Glutamate receptor, ionotropic, NMDA2B (epsilon 2) antibody; GRIN 2B antibody; GRIN2B antibody; hNR 3 antibody; hNR3 antibody; MGC142178 antibody; MGC142180 antibody; MRD6 antibody; N methyl D asparate receptor channel subunit epsilon 2 antibody; N methyl D aspartate receptor subtype 2B antibody; N methyl D aspartate receptor subunit 2B antibody; N methyl D aspartate receptor subunit 3 antibody; N-methyl D-aspartate receptor subtype 2B antibody; N-methyl-D-aspartate receptor subunit 3 antibody; NMDA NR2B antibody; NMDA R2B antibody; NMDAR2B antibody; NMDE2 antibody; NMDE2_HUMAN antibody; NME2 antibody; NR2B antibody; NR3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13224

Immunogen:Peptide sequence around phosphorylation site of Serine 1303(Q-H-S(p)-Y-D) derived from Human GRIN2B.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain.

Adams S.L., Biochim. Biophys. Acta 1260:105-108(1995).
Hess S.D., J. Pharmacol. Exp. Ther. 278:808-816(1996).
Mandich P., Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:GRIN2B

Research Areas:Neuroscience