Phospho-ERK 1/2 (Y205/222) (7A6) Mouse mAb

SKU: EM1342

Size: 100μL

Source:Mouse

Applications:IHC

Reactivity:Human, Mouse, Rat

Dilution:IHC 1:100-200

Immunogen:Synthetic Peptide

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Monoclonal

Isotype:IgG1

Concentration:1mg/mL

Observed_band(KD):44,42kDa

Human_gene_id:5594/5595

Human_swiss_prot_no:P27361/P28482

Subcellular_location:Nucleus

Other_name:MAPK, Mitogen-activated protein Kinase, PRKM2,MK01

Background:Mitogen-activated protein kinases (MAPKs) are a widely conserved family of serine/threonine protein kinases involved in many cellular programs such as cell proliferation, differentiation, motility, and death. The p44/42 MAPK (Erk1/2) signaling pathway can be activated in response to a diverse range of extracellular stimuli including mitogens, growth factors, and cytokines and is an important target in the diagnosis and treatment of cancer.