Phospho-CCR5 (Ser349) Antibody - Cat. #: CSB-PA942331

SKU: CSB-PA942331

Size :100ul

Clone Number:

Aliases:AM4 7 antibody; C C chemokine receptor type 5 antibody; C C CKR 5 antibody; C-C chemokine receptor type 5 antibody; C-C CKR-5 antibody; C-C motif chemokine receptor 5 A159A antibody; CC Chemokine Receptor 5 antibody; CC Chemokine Receptor Type 5 antibody; CC CKR 5 antibody; CC-CKR-5 antibody; CCCKR 5 antibody; CCCKR5 antibody; CCR 5 antibody; CCR-5 antibody; CCR5 antibody; CCR5 chemokine (C C motif) receptor 5 antibody; CCR5_HUMAN antibody; CD 195 antibody; CD195 antibody; CD195 Antigen antibody; Chemokine C C motif receptor 5 antibody; Chemokine receptor CCR5 antibody; CHEMR13 antibody; CKR 5 antibody; CKR5 antibody; CMKBR 5 antibody; CMKBR5 antibody; FLJ78003 antibody; HIV 1 Fusion Coreceptor antibody; HIV-1 fusion coreceptor antibody; HIV1 fusion coreceptor antibody; IDDM22 antibody; MIP-1 alpha receptor antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P51681

Immunogen:Peptide sequence around phosphorylation site of Serine 349 (E-I-S(p)-V-G) derived from Human CCR5.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:

Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.

Martin Oppermann, J. Biol. Chem., Mar 1999; 274: 8875.
Beatrix Pollok-Kopp, J. Biol. Chem., Jan 2003; 278: 2190 - 2198.
Ramtin Rahbar, J. Virol., Jul 2006; 80: 7245 - 7259.
H Olbrich, J. Leukoc. Biol., Mar 1999; 65: 281.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CCR5

Research Areas:Neuroscience?Cancer?Cardiovascular;Immunology;Microbiology?Signal transduction