Phospho-Casein Kinase II Alpha (Y255) Polyclonal Antibody

SKU: BT-PHS00391

Size:100μL

Background:Casein kinase II is a serine/threonine protein kinase that phosphorylates acidic proteins such as casein. It is involved in various cellular processes, including cell cycle control, apoptosis, and circadian rhythm. The kinase exists as a tetramer and is composed of an alpha, an alpha-prime, and two beta subunits. The alpha subunits contain the catalytic activity while the beta subunits undergo autophosphorylation. The protein encoded by this gene represents the alpha subunit. While this gene is found on chromosome 20, a related transcribed pseudogene is found on chromosome 11. Three transcript variants encoding two different proteins have been found for this gene.

Research_area:Cell Biology

Target_protein:CSNK2A1

applications:WB, IHC-p, ELISA

Reactivity:Human, mouse, rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Phospho-Casein Kinase IIalpha (Y255) Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):45144

UniProt accession:Human: P68400; Mouse: Q60737; Rat: P19139

Synonyms:CSNK2A1; CK2A1; Casein kinase II subunit alpha; CK II alpha

GeneID:Human: 1457; Mouse: 12995; Rat: 116549