Phospho-ATXN1 (Ser776) Antibody - Cat. #: CSB-PA597893

SKU: CSB-PA597893

Size :100ul

Clone Number:

Aliases:alternative ataxin1 antibody; Ataxin-1 antibody; ATX1 antibody; ATX1_HUMAN antibody; Atxn1 antibody; D6S504E antibody; OTTHUMP00000016065 antibody; SCA1 antibody; Spinocerebellar ataxia type 1 protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P54253

Immunogen:Peptide sequence around phosphorylation site of Serine 776(R-W-S(p)-A-P) derived from Human Ataxin 1.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ATXN1

Research Areas:Epigenetics and Nuclear Signaling?Neuroscience