PGDH/PHGDH Monoclonal Antibody

SKU: AN200135P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:PHGDH

Target Synonym:HEL-S;PHGDH;3-PGDH;3PGDH;HEL-S-113;NLS;NLS1;PDG;PGAD;PGD;PGDH;PHGDHD;SERA;PGDH3

Research Areas:Signal Transduction;Neuroscience;Metabolism

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:FCM;ICC/IF

Isotype:IgG2b

Clonality:Monoclonal

Clone NO.:11B11

UNIProt ID:O43175

Accession:

Background:This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known.

Concentration:1 mg/mL

Immunogen:Recombinant Human PGDH / PHGDH protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:ICC/IF 1:20-1:100;FCM 1:25-1:100;

Calculated MW:

ObservedMW: