PE-Cy5 Anti-Mouse/Rat Foxp3 Antibody(FJK-16s)

SKU: PC5-30055

Size: 50T

Target: Mouse/Rat Foxp3

Form: liquid

Conjugation: PE-Cy5

Conjugation Information: PE-Cy5 is designed to be excited by the Blue (488 nm), Green (532 nm) and yellow-green (561 nm) lasers and detected using an optical filter centered near 670 nm (e.g., a 690/50 nm bandpass filter).

Purification: 0

Purity: 0

Host: Rat

Clonality: Monoclonal

Clone ID: FJK-16s

Isotype: IgG2a, κ

Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: FOXP3 is a 47 kD transcription factor, also known as Forkhead box protein P3, Scurfin, JM2, or IPEX. It is proposed to be a master regulatory gene and more specific marker of T regulatory cells than most cell surface markers (such as CD4 and CD25). Transduced expression of FOXP3 in CD4⁺/CD25^- cells has been shown to induce GITR, CD103, and CTLA4 and impart a T regulatory cell phenotype. FOXP3 is mutated in X-linked autoimmunity-allergic dysregulation syndrome (XLAAD or IPEX) in humans and in "scurfy" mice. Overexpression of FOXP3 has been shown to lead to a hypoactive immune state suggesting that this transcriptional factor is a central regulator of T cell activity.

Immunogen: 0

Synonyms: IPEXJM2ScurfinZinc finger protein JM2|Forkhead box protein P3

Observed MW:

Uniprot ID: Q99JB6

Reactivity: Mouse;Rat

Tested Application: FC

Recommended dilution: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

image5:

Gene ID: 20371

Research Area:

Catagory: Flow cytometry Antibodies