PDK1 Monoclonal Antibody

SKU: BT-MCA1013

Size:100μL

Background:Pyruvate dehydrogenase (PDH) is a mitochondrial multienzyme complex that catalyzes the oxidative decarboxylation of pyruvate and is one of the major enzymes responsible for the regulation of homeostasis of carbohydrate fuels in mammals. The enzymatic activity is regulated by a phosphorylation/dephosphorylation cycle. Phosphorylation of PDH by a specific pyruvate dehydrogenase kinase (PDK) results in inactivation. Multiple alternatively spliced transcript variants have been found for this gene.

Research_area:Signal transduction; Cancer; Metabolism

Target_protein:PDK1

applications:WB, IHC-p, IF, ICC, FCM, ELISA

Reactivity:Human,Rat,Monkey

Clonality:Monoclonal

Clone ID:

Host:Mouse

Isotype:IgG

Gene Symbol/ Name:Pyruvate dehydrogenase (acetyl-transferring) kinase isozyme 1, mitochondrial

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):N/A

UniProt accession:Human: Q15118; Mouse: Q8BFP9; Rat: Q63065

Synonyms:PDK1; PDHK1; Pyruvate dehydrogenase (lipoamide) kinase isozyme 1; mitochondrial; Pyruvate dehydrogenase kinase isoform 1

GeneID:Human: 5163