PDGFRA/CD140a Monoclonal Antibody

SKU: AN200022P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:PDGFRA

Target Synonym:GAS;PDGFRA;CD140A;PDGFR-2;PDGFR2;GAS9;RHEPDGFRA;PDGF-RαAlpha platelet-derived growth factor receptor;Alpha-type platelet-derived growth factor receptor;CD_antigen: CD140a;CD140 antigen-like family member A;CD140a antigen;MGC74795;PDGF alpha chain;PDGFR 2;PDGFR alpha;PDGFRA/BCR fusion;PDGFR-alpha;PDGF-R-alpha;PGFRA;Platelet derived growth factor receptor;Platelet derived growth factor receptor 2;Platelet derived growth factor receptor alpha;Platelet derived growth factor receptor alpha polypeptide;Platelet-derived growth factor alpha receptor;Platelet-derived growth factor receptor 2;platelet-derived growth factor receptor A;Platelet-derived growth factor receptor alpha;platelet-derived growth factor receptor α;Rearranged in hypereosinophilia platelet derived growth factor receptor alpha fusion protein

Research Areas:Cardiovascular;Signal Transduction;Cancer

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:WB

Isotype:IgG2a

Clonality:Monoclonal

Clone NO.:1F10

UNIProt ID:P16234

Accession:

Background:This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers.

Concentration:1 mg/mL

Immunogen:Recombinant Human PDGFRA / CD140a protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:WB 1:500-1:1000;

Calculated MW:123 kDa

ObservedMW:123 kDa