PDE4B Rabbit Polyclonal Antibody

SKU: BT-AP11852

Size:100μL

Background:This gene is a member of the type IV| cyclic AMP (cAMP)-specific| cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms.

Research_area:Signal transduction

Target_protein:PDE4B

applications:WB

Reactivity:Human, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:PDE4B

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):80960

UniProt accession:Human: Q07343; Rat: P14646

Synonyms:PDE4B

GeneID:Human: 5142; Rat: 24626