PCNA Monoclonal Antibody(12D10)

SKU: BT-MCA0068

Size:100μL

Background:The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome.

Research_area:Cancer; Cell biology; Epigenetics and nuclear signaling; Tags & cell markers

Target_protein:PCNA

applications:WB, IF, ICC, IHC-p

Reactivity:Human,Rat,Mouse

Clonality:Monoclonal

Clone ID:

Host:Mouse

Isotype:IgG

Gene Symbol/ Name:Proliferating cell nuclear antigen

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):28769

UniProt accession:Human: P12004; Mouse: P17918; Rat: P04961

Synonyms:PCNA; Proliferating cell nuclear antigen; PCNA; Cyclin

GeneID:Human: 5111; Mouse: 18538; Rat: 25737