PAX4 Antibody - Cat. #: CSB-PA017490ESR1HU

SKU: CSB-PA017490ESR1HU

Size :50ul

Clone Number:

Aliases:KPD antibody; MGC129960 antibody; MODY9 antibody; Paired box 4 antibody; Paired box gene 4 antibody; paired box homeotic gene 4 antibody; Paired box protein Pax-4 antibody; Paired domain gene 4 antibody; Pax4 antibody; PAX4_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O43316

Immunogen:Recombinant Human Paired box protein Pax-4 protein (50-200AA)

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200

Background:Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Competes with PAX6 for this same promoter binding site. Isoform 2 appears to be a dominant negative form antagonizing PAX4 transcriptional activity.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PAX4

Research Areas:Epigenetics and Nuclear Signaling; Developmental biology