PAK6 Antibody - Cat. #: CSB-PA865108ESR2HU

SKU: CSB-PA865108ESR2HU

Size :50ul

Clone Number:

Aliases:CDKN1A activated kinase 6 antibody; EC 2.7.1.37 antibody; p21 activated protein kinase 6 antibody; p21 protein (Cdc42/Rac)-activated kinase 6 antibody; p21(CDKN1A) activated kinase 6 antibody; p21-activated kinase 6 antibody; p21activated kinase 6 antibody; PAK 5 antibody; PAK 6 antibody; PAK-5 antibody; PAK-6 antibody; PAK5 antibody; Pak6 antibody; PAK6_HUMAN antibody; Serine threonine protein kinase PAK 6 antibody; Serine/threonine protein kinase PAK 6 antibody; Serine/threonine protein kinase PAK6 antibody; Serine/threonine-protein kinase PAK 6 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9NQU5

Immunogen:Recombinant Human Serine/threonine-protein kinase PAK 6 protein (1-270AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Serine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR-mediated transcription. Inhibits also ESR1-mediated transcription. May play a role in cytoskeleton regulation by interacting with IQGAP1. May protect cells from apoptosis through phosphorylation of BAD.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PAK6

Research Areas:Signal transduction