p63 Polyclonal Antibody

SKU: E-AB-70281

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:p63

Target Synonym:AIS;Amplified in squamous cell carcinoma;B(p51A);B(p51B);Chronic ulcerative stomatitis protein;CUSP;DN p63 alpha 1;DNp63;EEC3;id:ibd3516;Keratinocyte transcription factor;Keratinocyte transcription factor KET;KET;LMS;MGC115972;MGC192897;NBP;OFC8;OTTHUMP00000209732;OTTHUMP00000209733;OTTHUMP00000209734;OTTHUMP00000209735;OTTHUMP00000209737;OTTHUMP00000209738;OTTHUMP00000209739;OTTHUMP00000209740;OTTHUMP00000209741;OTTHUMP00000209742;OTTHUMP00000209743;OTTHUMP00000209744;p40;p51;P51/P63;p53-related protein p63;p53CP;p63;P63;p73H;p73L;RHS;SHFM4;TAp63alpha;TP53CP;TP53L;TP63;TP73L;Transformation related protein 63;Transformation-related protein 63;Trp53rp1;Trp63;Tumor protein 63;Tumor protein p53-competing protein;Tumor protein p53-like;Tumor protein p63;Tumor protein p63 deltaN isoform delta;Tumor protein p73;Tumor protein p73-like

Research Areas:Cancer;Cell Biology;Epigenetics and Nuclear Signaling

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q9H3D4,O88898,Q9JJP6

Accession:

Background:TP63,also named KET,P63,P73H,P73L and TP73L,belongs to the p53 family. It is a homologue of the tumor suppressor p53 and p73 genes. It is involved in malignancy acquisition and maintenance of cells. Unlike p53,the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis. TP63 acts as a sequence specific DNA binding transcriptional activator or repressor. TP63 has 12 isoforms with MW 40kd(P40),50kd(P60),63kd(P63) and 73kd(P73L). It is Nuclear stain.

Concentration:330 μg/mL

Immunogen:Recombinant protein corresponding to Mouse P63

Buffer:PBS with 0.02% sodium azide, 1% protective protein and 50% glycerol, pH7.4

Purification method:Affinity purification

Dilution:WB 1:500-1:2000

Calculated MW:50-75kDa

ObservedMW:75kDa