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Gene Bio Systems

OPRK1 Antibody - Cat. #: CSB-PA016359OA01HU

OPRK1 Antibody - Cat. #: CSB-PA016359OA01HU

CSB-PA016359OA01HU

€331,95 EUR
€331,95 EUR
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Size :50ul

Clone Number:

Aliases:K-OR-1 antibody; Kappa opioid receptor antibody; Kappa type opioid receptor antibody; Kappa-type opioid receptor antibody; KOR 1 antibody; KOR antibody; KOR-1 antibody; Opiate receptor kappa 1 antibody; Opiate receptor; kappa 1 antibody; Opioid receptor; kappa 1 antibody; OPRK 1 antibody; OPRK antibody; OPRK_HUMAN antibody; OPRK1 antibody; Oprk2 antibody; R21 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P41145

Immunogen:Peptide sequence from Human Kappa-type opioid receptor protein (31-50AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background:G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:OPRK1

Research Areas:Neuroscience

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