OLFM3 Antibody - Cat. #: CSB-PA201620

SKU: CSB-PA201620

Size :50ul

Clone Number:

Aliases:OLFM3 antibody; NOE3 antibody; UNQ1924/PRO4399 antibody; Noelin-3 antibody; Olfactomedin-3 antibody; Optimedin antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q96PB7

Immunogen:Fusion protein of Human OLFM3

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; ELISA:1:1000-1:2000, WB:1:200-1:1000

Background:OLFM3 (olfactomedin 3), also known as NOE3, is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:OLFM3

Research Areas:Neuroscience;Signal transduction