O-FucT-1 rabbit pAb

SKU: ES5350

Size: 100μL

Source:Rabbit

Applications:WB;IHC;IF;ELISA

Reactivity:Human;Mouse;Rat

Dilution:Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human POFUT1. AA range:331-380

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):44kD

Human_gene_id:23509

Human_swiss_prot_no:Q9H488

Subcellular_location:Endoplasmic reticulum .

Other_name:POFUT1; FUT12; KIAA0180; GDP-fucose protein O-fucosyltransferase 1; Peptide-O-fucosyltransferase 1; O-FucT-1

Background:This gene encodes a member of the glycosyltransferase O-Fuc family. This enzyme adds O-fucose through an O-glycosidic linkage to conserved serine or threonine residues in the epidermal growth factor-like repeats of a number of cell surface and secreted proteins. O-fucose glycans are involved in ligand-induced receptor signaling. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008],