NTRK3 Monoclonal Antibody

SKU: BT-MCA3962

Size:100μL

Background:NTRK3 (neurotrophic tyrosine kinase, receptor, type 3), it is a member of the neurotrophic tyrosine receptor kinase (NTRK) family and plays an important role in the development and maintenance of neural tissues. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.

Research_area:Neuroscience

Target_protein:NTRK3

applications:IHC

Reactivity:Human

Clonality:Monoclonal

Clone ID:7H6

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:NTRK3

Immunogen:Purified recombinant extracellular fragment of human NTRK3 (aa32-429) fused with hIgGFc tag expressed in HEK293 cells.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):94kDa

UniProt accession:Q16288

Synonyms:TRKC, gp145(trkC)

GeneID:4916