NPY6R Polyclonal Antibody

SKU: BT-AP12000

Size:100μL

Background:Could be the product of a pseudogene. According to PubMed:97066888, PubMed:97066971 and PubMed:9013614, the human NPY6R gene is an expressed pseudogene containing a premature stop codon and encoding a non-functional truncated protein missing the last transmembrane domain. A single base pair deletion relative to the mouse ortholog, results in a truncated protein lacking the seventh transmembrane domain.,When expressed, is unable to bind pancreatic polypeptide (PP), neuropeptide Y (NPY), or peptide YY (PYY), suggesting that either it is functionally inactive or that it may have acquired a pancreatic polypeptide-independent function.,Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in heart, skeletal muscle, gastrointestinal tissues, spleen, brain and adrenal glands.,

Research_area:Neuroscience; Epigenetics and nuclear signaling

Target_protein:NPY6R

applications:WB, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Putative neuropeptide Y receptor type 6

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q99463; Mouse: Q61212

Synonyms:Putative neuropeptide Y receptor type 6 ;NPY6-R;NPY Y1-like receptor;Putative pancreatic polypeptide receptor 2;PP2

GeneID: