NMNAT1 Antibody - Cat. #: CSB-PA864012ESR1HU

SKU: CSB-PA864012ESR1HU

Size :50ul

Clone Number:

Aliases:EC 2.7.7.1 antibody; LCA9 antibody; Leber's congenital amaurosis 9 antibody; NaMN adenylyltransferase 1 antibody; nicotinamide nucleotide adenylyltransferase 1 antibody; Nicotinamide-nucleotide adenylyltransferase 1 antibody; Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 antibody; nicotinate nucleotide adenylyltransferase 1 antibody; Nicotinate-nucleotide adenylyltransferase 1 antibody; NMN adenylyltransferase 1 antibody; NMN/NaMN adenylyltransferase 1 antibody; NMNA1_HUMAN antibody; Nmnat 1 antibody; Nmnat1 antibody; OTTHUMP00000001731 antibody; OTTHUMP00000001732 antibody; OTTHUMP00000035892 antibody; PNAT 1 antibody; PNAT1 antibody; pyridine nucleotide adenylyltransferase 1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9HAN9

Immunogen:Recombinant Human Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 protein (1-279AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, prefers NAD(+) and NaAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate (NHD) and nicotinamide guanine dinucleotide (NGD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NaADP(+). Protects against axonal degeneration following mechanical or toxic insults.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NMNAT1

Research Areas:Epigenetics and Nuclear Signaling; Neuroscience; Cancer; Metabolism; Signal transduction