NFKBID Antibody - Cat. #: CSB-PA173796

SKU: CSB-PA173796

Size :50ul

Clone Number:

Aliases:NFKBID antibody; IKBNS antibody; NF-kappa-B inhibitor delta antibody; I-kappa-B-delta antibody; IkB-delta antibody; IkappaBdelta antibody; IkappaBNS antibody; T-cell activation NFKB-like protein antibody; TA-NFKBH antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8NI38

Immunogen:Fusion protein of Human NFKBID

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100

Background:May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.I?BNS, the nuclear I?B-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.I?BNS has been identified as a member of the I?B family of NF-?B inhibitors, which undergoes induction upon TCR signaling. I?BNS mediates both positive and negative gene regulation, depending on individual cell type and/or cytokine.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NFKBID

Research Areas:Epigenetics and Nuclear Signaling;Immunology;Signal transduction