NFAT5 rabbit pAb

SKU: ES8599

Size: 100μL

Source:Rabbit

Applications:WB;IHC;IF;ELISA

Reactivity:Human;Rat;Mouse

Dilution:WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000

Immunogen:Synthetic peptide from human protein at AA range: 212-284

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:10725

Human_swiss_prot_no:O94916

Subcellular_location:Nucleus . Cytoplasm . Nuclear distribution increases under hypertonic conditions. .

Other_name:Nuclear factor of activated T-cells 5 (NF-AT5;T-cell transcription factor NFAT5;Tonicity-responsive enhancer-binding protein;TonE-binding protein;TonEBP)

Background:The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],