NEFL Monoclonal Antibody

SKU: BT-MCA3752

Size:100μL

Background:Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.

Research_area:Neuroscience

Target_protein:NEFL

applications:WB, IHC, ICC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:2G10

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:NEFL

Immunogen:Purified recombinant fragment of human NEFL expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):62kDa

UniProt accession:P07196

Synonyms:NFL, NF-L, NF68, CMT1F, CMT2E

GeneID:4747