Neddylin Polyclonal Antibody

SKU: BT-AP05872

Size:100μL

Background:NEDD8 is a Protein Coding gene. Among its related pathways are Signaling by GPCR and p53 pathway (Pathway Interaction Database). Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. Gene Ontology (GO) annotations related to this gene include ubiquitin protein ligase binding. An important paralog of this gene is UBA52.

Research_area:Cell Biology

Target_protein:NEDD8

applications:WB, IHC-p, ELISA

Reactivity:Human, Mouse, Rat, Monkey

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Neddylin Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):9072

UniProt accession:Human: Q15843; Mouse: P29595; Rat: Q71UE8

Synonyms:NEDD8; NEDD8; Neddylin; Neural precursor cell expressed developmentally down-regulated protein 8; NEDD-8; Ubiquitin-like protein Nedd8

GeneID:Human: 4738; Mouse: 18002; Rat: 25490