NDEL1 Antibody - Cat. #: CSB-PA872414ESR1HU

SKU: CSB-PA872414ESR1HU

Size :50ul

Clone Number:

Aliases:A. nidulans antibody; DKFZp451M0318 antibody; ENDOOLIGOPEPTIDASE A antibody; EOPA antibody; MITAP 1 antibody; MITAP1 antibody; Mitosin associated protein 1 antibody; Mitosin associated protein MITAP1 antibody; Mitosin-associated protein 1 antibody; Ndel 1 antibody; NDEL1 antibody; NDEL1_HUMAN antibody; Nuclear distribution gene E like homolog 1 antibody; Nuclear distribution protein nudE like 1 antibody; Nuclear distribution protein nudE-like 1 antibody; NUDE like protein antibody; NudE nuclear distribution gene E homolog like 1 A. nidulans antibody; NudE nuclear distribution gene E homolog like 1 antibody; NUDEL antibody; Protein Nudel antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9GZM8

Immunogen:Recombinant Human Nuclear distribution protein nudE-like 1 protein (1-345AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Required for organization of the cellular microtubule array and microtubule anchoring at the centrosome. May regulate microtubule organization at least in part by targeting the microtubule severing protein KATNA1 to the centrosome. Also positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus ends. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the centripetal motion of secretory vesicles and the coupling of the nucleus and centrosome. Also required during brain development for the migration of newly formed neurons from the ventricular/subventricular zone toward the cortical plate. Plays a role, together with DISC1, in the regulation of neurite outgrowth. Required for mitosis in some cell types but appears to be dispensible for mitosis in cortical neuronal progenitors, which instead requires NDE1. Facilitates the polymerization of neurofilaments from the individual subunits NEFH and NEFL.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NDEL1

Research Areas:Neuroscience; Cell biology; Signal transduction