NCOA3 Monoclonal Antibody

SKU: BT-MCA4060

Size:100μL

Background:NCOA3: nuclear receptor coactivator 3. The protein encoded by this gene is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Two transcript variants encoding different isoforms have been found for this gene. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:NCOA3

applications:

Reactivity:Human

Clonality:Monoclonal

Clone ID:2C11B12

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:NCOA3

Immunogen:Purified recombinant fragment of NCOA3 (aa1-200) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):

UniProt accession:Q9Y6Q9

Synonyms:ACTR, AIB1

GeneID:8202