NCAM1 Antibody - Cat. #: CSB-PA960581

SKU: CSB-PA960581

Size :100ul

Clone Number:

Aliases:antigen MSK39 identified by monoclonal antibody 5.1H11 antibody; antigen recognized by monoclonal antibody 5.1H11 antibody; CD56 antibody; cell adhesion molecule, neural, 1 antibody; MSK 39 antibody; MSK39 antibody; N-CAM-1 antibody; NCAM 1 antibody; NCAM antibody; NCAM C antibody; NCAM-1 antibody; NCAM1 antibody; NCAM1_HUMAN antibody; NCAMC antibody; Neural cell adhesion molecule 1 antibody; Neural cell adhesion molecule NCAM antibody; OTTHUMP00000235666 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P13591

Immunogen:Peptide sequence around aa.850~854(Q-T-K-E-N)derived from Human CD56(NCAM).

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:NCAM (neural cell adhesion molecule, CD56) is an adhesion glycoprotein with five extracellular immunoglobulin-like domains followed by two fibronectin type III repeats. Structural diversity is introduced by alternative splicing resulting in different cytoplasmic domains (1). NCAM mediates neuronal attachment, neurite extension and cell-cell interactions through homo and heterophilic interactions. PSA (polysialic acid) post-translationally modifies NCAM and increases the metastatic potential of small cell lung carcinoma, Wilms+ tumor, neuroblastoma and rhabdomyosarcoma (2). CD56 and CD16 are commonly used to identify NK cells although some cells with the T cell markers CD3 and CD4 also express CD56 (3).

Cunningham, B. A. et al. (1987) Science 236, 799-806.
Seidenfaden, R. et al. (2003) Mol. Cell. Biol. 23, 5908-5918.
Robertson, M.J. and Ritz, J. (1990) Blood 76, 2421-2438.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:NCAM1

Research Areas:Neuroscience;Signal transduction?Stem cells