Nampt Antibody - Cat. #: CSB-PA015422LA01RA

SKU: CSB-PA015422LA01RA

Size :50ul

Clone Number:

Aliases:Nampt antibody; Pbef1 antibody; Nicotinamide phosphoribosyltransferase antibody; NAmPRTase antibody; Nampt antibody; EC 2.4.2.12 antibody; Pre-B-cell colony-enhancing factor 1 homolog antibody; PBEF antibody; Visfatin antibody

Product Type:Polyclonal Antibody

Immunogen Species:Rattus norvegicus (Rat)

UniProt ID:Q80Z29

Immunogen:Recombinant Rat Nampt protein (231-491AA)

Raised in:Rabbit

Species Reactivity:Rat, Human

Tested Applications:ELISA, WB; Recommended dilution: WB:1:1000-1:5000

Background:Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Antigen Affinity purified & Affinity purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:Nampt

Research Areas:Epigenetics and Nuclear Signaling