MTM1 antibody , Cat. # FNab05406

SKU: FNab05406

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate(PI3P) and phosphatidylinositol 3,5-bisphosphate(PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine-and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis.

Immunogen:myotubularin 1

Synonyms:CG2

Observed MW:63 kDa

Uniprot ID:Q13496

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC

Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200

Gene ID:4534

Research Area:Stem Cells, Metabolism, Developmental biology