MTM1 Antibody - Cat. #: CSB-PA614418ESR2HU

SKU: CSB-PA614418ESR2HU

Size :50ul

Clone Number:

Aliases:AF073996 antibody; CG2 antibody; CNM antibody; KIAA4176 antibody; mKIAA4176 antibody; Mtm antibody; Mtm1 antibody; MTM1_HUMAN antibody; MTMX antibody; Myotubular myopathy 1 antibody; Myotubularin antibody; XLMTM antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13496

Immunogen:Recombinant Human Myotubularin protein (484-603AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Lipid phosphatase which dephosphorylates phosphatidylinositol 3-monophosphate (PI3P) and phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2). Has also been shown to dephosphorylate phosphotyrosine- and phosphoserine-containing peptides. Negatively regulates EGFR degradation through regulation of EGFR trafficking from the late endosome to the lysosome. Plays a role in vacuolar formation and morphology. Regulates desmin intermediate filament assembly and architecture. Plays a role in mitochondrial morphology and positioning. Required for skeletal muscle maintenance but not for myogenesis.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MTM1

Research Areas:Cancer; Cell biology; Metabolism; Signal transduction; Stem cells