MSH4 Antibody - Cat. #: CSB-PA987494

SKU: CSB-PA987494

Size :50ul

Clone Number:

Aliases:hMSH4 antibody; MSH 4 antibody; MSH4 antibody; MSH4_HUMAN antibody; MutS homolog 4 (E. Coli) antibody; MutS homolog 4 antibody; MutS protein homolog 4 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O15457

Immunogen:Fusion protein of Human MSH4

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC; ELISA:1:2000-1:10000, IHC:1:100-1:300

Background:This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:MSH4

Research Areas:Epigenetics and Nuclear Signaling